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Full capacity crowds are set to return in what will be an exhilarating 2021 NFL season and every single side will be more determined than ever to win this year's Super Bowl and give something back to the fans that have endured a challenging 18 months where following your team was strictly limited to the couch.
Having failed to retain the Super Bowl with a crushing defeat against Tampa Bay Buccaneers, Kansas City Chiefs, guided by GOAT-in-waiting Patrick Mahomes, will be determined to regain their status as the champions this season. At just 25-years-old, Mahomes is establishing himself as the next name in lights and with him set for another big season, it's no surprise that the Chiefs are the 5/1 favorites with leading oddsmaker Betfair to win their third Super Bowl.
Holders Tampa Bay Buccaneers, propelled by veteran Tom Brady, present the biggest challenge to the Chiefs' charge and they're 13/2 to retain the title. Brady ended a 20-season love affair with the New England Patriots and joined the Buccaneers during a pandemic and guided them to a second Super Bowl win, which makes you wonder what he can do with an undisturbed pre-season.
If a master vs apprentice matchup between Brady and Mahomes is your idea of a final, then the Chiefs vs Buccaneers to meet in February is 10/1.
The GOAT will keep a close eye on his records and Mahomes' career develops, but at 44 years young, Brady will be focused on plotting his way to a fourth regular season MVP award. Brady is 14/1 to light up the regular season, while fellow three-time winner Aaron Rodgers is 15/2.
New kid on the block, Mahomes, is the 9/2 favorite to be the regular season MVP to add to his triumph and MVP performance in Super Bowl LIV.
Last season's regular season MVP Aaron Rodgers is 15/2 to repeat that feat with the Packers and Bills quarterback Josh Allen is 12/1.

Betfair — Super Bowl LVI winner odds
Kansas City Chiefs - 5/1
Tampa Bay Buccaneers - 13/2
Green Bay Packers, Buffalo Bills - 10/1
Cleveland Browns, San Francisco 49ers, Baltimore Ravens, Los Angeles Rams - 14/1
Seattle Seahawks - 18/1
Tennessee Titans - 20/1
Miami Dolphins, Dallas Cowboys, New Orleans Saints, Los Angeles Chargers, Indianapolis Colts - 25/1
New England Patriots - 33/1
Denver Broncos, Arizona Cardinals, Minnesota Vikings, Pittsburgh Steelers - 40/1
Atlanta Falcons, Washington Football Team, Chicago Bears - 50/1
Las Vegas Raiders, New York Giants - 66/1
Carolina Panthers, Philadelphia Eagles - 80/1
New York Jets, Cincinnati Bengals, Jacksonville Jaguars - 100/1
Detroit Lions - 150/1
Houston Texans - 250/1
Betfair — Regular Season MVP odds
Patrick Mahomes - 9/2
Aaron Rodgers - 15/2
Josh Allen - 12/1
Tom Brady, Lamar Jackson - 14/1
Matthew Stafford - 16/1
Russell Wilson, Dak Prescott - 17/1
Justin Herbert, Kyler Murray - 20/1
Baker Mayfield - 22/1
Matt Ryan - 33/1
Carson Wentz, Ryan Tannehill - 35/1
Betfair — AFC winner odds
Kansas City Chiefs - 5/2
Buffalo Bills - 11/2
Baltimore Ravens - 13/2
Cleveland Browns - 8/1
Tennessee Titans - 12/1
Los Angeles Chargers, Indianapolis Colts, Miami Dolphins, New England Patriots - 16/1
Pittsburgh Steelers - 20/1
Denver Broncos - 25/1
Las Vegas Raiders - 33/1
New York Jets, Jacksonville Jaguars, Cincinnati Bengals - 66/1
Houston Texans - 150/1
Betfair — NFC winner odds
Tampa Bay Buccaneers - 3/1
Green Bay Packers - 11/2
San Francisco 49ers - 13/2
Los Angeles Rams - 7/1
Seattle Seahawks - 10/1
Dallas Cowboys - 14/1
New Orleans Saints - 16/1
Minnesota Vikings - 18/1
Arizona Cardinals, Washington Football Team - 20/1
Chicago Bears, Atlanta Falcons - 25/1
New York Giants - 33/1
Carolina Panthers, Philadelphia Eagles - 50/1
Detroit Lions - 100/1